A Brief History Of The Health Support Uses Of Silver
Hippocrates, the "father of medicine", wrote that silver had beneficial healing and anti-disease properties. The Phoenicians are said to have stored water, wine, and vinegar in silver bottles to prevent spoiling. In the early 1900s, people would put silver sixpences in milk bottles to prolong the milk's freshness. Silver has had some medicinal uses going back for centuries. Physicians used it as an eyedrop for ophthalmic problems, for various infections, and sometimes internally for diseases such as epilepsy and gonorrhea, and the common cold. In the early 1900s, Silver gained regulatory approval as an antimicrobial agent. Prior to the introduction of antibiotics, colloidal silver was used as a germicide and disinfectant.
In World War I, before the advent of antibiotics, silver compounds were used to prevent and treat infections. Silver compounds continue to be used in external preparations as antiseptics including silver nitrate, which can be used in dilute solution as eyedrops to prevent conjunctivitis in newborn babies. Silver nitrate is also sometimes used in dermatology in solid stick form as a caustic ("lunar caustic") to treat certain skin conditions such as corns and warts.
With the introduction of antibiotics in the 1940s, the use of silver as an antimicrobial agent diminished. As a result, colloidal silver was replaced by other, more effective silver compounds.
According to Atiyeh et al. (2007), "The gold standard in topical burn treatment is silver sulfadiazine (Ag-SD), a useful antibacterial agent for burn wound treatment". They do note, however, that silver-impregnated dressings do sometimes result in a slower healing process. Silver sulfadiazine cream (SSD Cream) replaced colloidal silver as the most common delivery system for using silver on the surface of burn wounds to control infection in the 1970s.
Electrolytically dissolved silver has been used as a water disinfecting agent. Silver was added as a disinfectant to the drinking water supplies of Russian Mir orbital station and the International Space Station. The World Health Organization includes silver in a colloidal state produced by electrolysis of silver electrodes in water, and colloidal silver in water filters as two of a number of water disinfection methods specified to provide safe drinking water in developing countries. Along these lines, a ceramic filtration system coated with silver particles has been created by Ron Rivera of Potters for Peace and used in developing countries for water disinfection.
Current alternative medicine use
From approximately 1990, there has been a resurgence of the promotion of colloidal silver as an alternative medicine treatment, marketed with claims of it being an essential mineral supplement, or that it can prevent or treat numerous diseases like cancer, diabetes, HIV/AIDS, and herpes, as well as tuberculosis. Although colloidal silver products are legally available at health food stores in the United States and Australia and are marketed over the Internet as a dietary supplement, it is illegal in the U.S. and Australia for marketers to make such claims of medical effectiveness for colloidal silver. There is no medical evidence that colloidal silver is effective for any of these claimed indications. Silver is not an essential mineral in humans; there is no dietary requirement for silver, and no such thing as a silver "deficiency".
The medical uses of silver include its incorporation into wound dressings to treat external infections, and its use as an antiseptic and disinfectant in medical appliances. There is however insufficient evidence to support its use in wound healing. Silver is also promoted within alternative medicine in the form of colloidal silver, though it has never been proven safe and effective. According to medical journals from around the world, Colloidal Silver disables the particle enzyme that all one-celled bacteria, fungi and viruses use for their oxygen metabolism. Colloidal Silver co-mingles with the blood and enters the cells to seek out and destroy harmful organisms. It suffocates them in six (6) minutes or less. This phenomenon of Colloidal Silver has been successful tested at the UCLA Medical Labs where it killed every virus on which it was tested. Tests prove, due to the high absorption in the small intestine, the friendly bacteria in the large intestines are not affected. Trace amounts protect and strengthen the immune system.
All bacterial, viral and fungal organisms are killed within 6 minutes of contact. Higher silver content in the body causes faster and more frequent contract with these organisms. No disease can live in the presence of simple silver. The following is a partial list of more than 650 diseases that Colloidal Silver has been successfully used against Acne, Arthritis, Athlete's Foot, Toxemia, Blood Poisoning, Burns, Cancer, conjunctivitis, Dermatitis, Diabetes, Dysentery, Eczema, Fibrositis, Gastritis, Gonorrhea, Impetigo., Keratitis, Leprosy, Lupus, Pymphagitis, Malaria, Meningitis, Neurathenia, Pleursy, Pneumonia, Prostate, Psoriasis, Pruritis Ani, Ophthalmia, Ringworm, Rhinitis Rosacea, Scarlet Fever, Seborrhea, Septicemia, Shingles, Skin Cancer, Straph Infection, Herpes Virus, Ulcers, Strep, Tonsillitis, Trenchfoot, Tuberculosisi, Virus Warts, Whooping Cough and Yeast Infections.
The silver ion (Ag+) is bioactive and in sufficient concentration readily kills bacteria in vitro. Silver also kills bacteria in external wounds in living tissue and therefore physicians use wound dressings containing silver sulfadiazine (Ag-SD) or silver nano-materials to treat external infections. Wound dressings containing silver are increasing in importance due to the recent increase of antibiotic-resistant bacteria such as methicillin-resistant Staphylococcus aureus. The disinfectant properties of silver are used in medical applications, such as urinary catheters and endotracheal breathing tubes, where the silver content is effective in reducing incidences of catheter-related urinary tract infections and ventilator-associated pneumonia (VAP) respectively. Silver is also used in bone prostheses, reconstructive orthopaedic surgery and cardiac devices, as well as on surfaces and fabrics to reduce the spread of infection.
Since the 1990s, "colloidal silver", a liquid suspension of microscopic silver particles, has been marketed as an alternative medicine, often claiming impressive "cure-all" qualities. The effectiveness of these products has never been scientifically proven, and in some jurisdictions it is, therefore, currently illegal to include such claims in product advertisements.
The US Food and Drug Administration has approved the use of a range of different silver-impregnated wound dressings.
Laboratory studies at the Biochemical Materials Research and Development Center of Jiaxing College, China, have shown that silver-containing alginate fibres provide a sustained release of silver ions when in contact with wound exudates, and are “highly effective against bacteria” A study administered by the Hull York Medical School found that an antimicrobial barrier dressing containing silver provided “a highly effective and reliable barrier to the spread of MRSA into the wider hospital.”
More recently, dressings incorporating nanocrystalline silver or activated silver-impregnated substances have become available, which deliver higher concentrations of the active silver ion. As of 2006, more "than 10 dressings containing pure silver" were available. In particular, silver is being used with alginate, a naturally occurring biopolymer derived from seaweed, in a range of products designed to prevent infections as part of wound management procedures, particularly applicable to burn victims
Wound dressings containing silver are increasing in importance due to the increase of antibiotic-resistant bacteria, which has imposed clinical limits on the use of antibiotics. Chopra states that topical silver is regaining popularity in the management of open wounds, “due largely to the spread of methicillin-resistant Staphylococcus aureus and the resultant reduction in first-line antibiotic prescribing”. Chopra also expresses the concern that “There is a need for silver MIC levels and breakpoints to be developed and standardized.” He does however conclude that “Some silver-based dressings appear to provide an effective alternative to antibiotics in the management of wound infection.”
Silver has proven antimicrobial activity that includes antibiotic-resistant bacteria. It has a broad spectrum of antimicrobial activity, with minimal toxicity toward mammalian cells at low concentrations, and has a less likely tendency than antibiotics to induce resistance due to its activity at multiple bacterial target sites.
Silver compounds in medical appliances
A study on the use of silver-alloy catheters by the University of Michigan School of Medicine concluded that “The data supporting the use of silver alloy urinary catheters to reduce urinary catheter-related bacteriuria is reasonably strong. The study also concluded that silver alloy catheters are more effective than standard catheters for reducing bacteriuria in adults in hospital having short-term catheterization, and that, although they cost about $6 more than standard urinary catheters, they may be worth the extra cost, since catheter-related infection is a common cause of nosocomial infection and bacteremia. Related meta-analysis also clarified discrepant results among earlier trials of silver-coated urinary catheters by revealing that silver alloy catheters are significantly more effective in preventing urinary tract infections than are silver oxide catheters. These conclusions are supported by, among others, studies by the University Hospitals Leuven, Belgium and the University Hospital for Anesthesiology and Surgical Intensive Care, Halle, Germany.
In 2007, AGC Flat Glass Europe introduced the first antibacterial glass to fight hospital-caught infection: It is covered with a thin layer of silver Ionizable silver is also incorporated into fabrics to reduce the spread of bacteria.
Ventilator-associated pneumonia (VAP) causes substantial morbidity. A 2008 study by Kollef et al concluded that “Patients receiving a silver-coated endotracheal tube had a statistically significant reduction in the incidence of VAP and delayed time to VAP occurrence compared with those receiving a similar, uncoated tube. In addition, the U.S. Food and Drug Administration (FDA) has recently approved an endotracheal breathing tube with a fine coat of silver for use in mechanical ventilation, after studies found it reduced the risk of ventilator-associated pneumonia.
Government Regulation - We want you to read this so as to comply with the FDA rulings regarding Colloidal Silver
In August 1999, the U.S. Food and Drug Administration (FDA) banned colloidal silver sellers from claiming any therapeutic or preventive value for the product, noting that colloidal silver was being marketed for numerous diseases without evidence of safety or effectiveness. Before issuing its decision, the FDA requested comments and evidence from the public and from marketers of colloidal silver. In response, the FDA received isolated case reports and testimonials from marketers and consumers, but did not receive any scientific evidence. The FDA concluded: "None of the comments presented any evidence of safety or effectiveness beyond personal experience." As a result, the product now has the status of a dietary supplement in the US; it can be promoted with general "structure-function" claims, but cannot be marketed as preventing or treating any illness. Following this ruling, the FDA has issued numerous warnings to Internet sites that have continued to promote colloidal silver as an antibiotic or for other medical purposes.
Mesosilver - A Scientific Advancement
Mesosilver is 0.9999 pure silver in colloidal form, a true silver colloid
· All natural mineral supplement in the form of nanoparticle colloidal silver.
· Highest particle surface area for maximum effectiveness. Up to 600 times greater than other products. See the Comparison Table Below for details.
· No adverse side effects have ever been reported.
· Highest bioavailability of any colloidal silver product due to sub-nanometer size particles.
· True colloidal silver. Colloid means silver particles, not silver ions.
· Smallest silver nanoparticles whose diameter typically measure 0.65 nm or less.
· Highest nanoparticle concentration, 80% particles (typical). Others are only 10%, see When is Colloidal Silver Not A Colloid?
· Not ionic silver like other products claiming to be colloidal silver.
· High purity silver 0.9999. Beyond 4 nines is meaningless.
· No potentially dangerous protein additives (mild protein).
· Made using the highest purity, sterile reagent grade deionized water.
· Concentration: 20 ppm (minimum) total silver.
· MesoSilver is non-toxic. See Material Safety Data Sheet (MSDS).
· Does not interact or interfere with any medications.
· Mesosilver will not cause argyria, a discoloration of the skin caused by some forms of silver. Argyria is caused by silver protein products.
· Contains only pure water and pure silver.
· Highest particle surface area of any colloidal silver product available.
· Slight metallic taste is normal. See FAQ page for more details on taste.
· Does not require refrigeration after opening
· Infinite shelf life.
· Manufactured in an FDA registered facility.
Mesosilver brand colloidal silver is the result of thousands of hours of research and development conducted at the Colloidal Science Laboratory, Inc. (CSL) over a period of several years. Purest Colloids, Inc. is the exclusive worldwide producer of MesoSilver. The resulting product, with a particle surface area many times greater than other products of this type, provides more usable silver to the body. To better understand how to compare colloidal silver products, see How To Compare Colloidal Silver Products.
Colloidal Silver Effectiveness
What is particle surface area?
In the world of colloids, particle surface area is the property of colloidal silver that directly determines the ability of the colloid to react with its environment. Therefore the effectiveness of colloidal silver is predicated on particle surface area. The higher the particle surface area the more effective the colloidal silver.
Particle surface area is defined as the total surface area in square centimeters (cm2) of all the particles in one milliliter (mL) of colloid. In the world of chemistry the ability of one substance to interact with other substances in its environment is predicated on the surface area of the substances or stated another way, reactivity increases with increasing surface area. A larger value of particle surface area increases the reactivity of the colloid.
In the booklet "Silver Colloids" Professor Gibbs wrote "The size of the particles in the colloidal silver suspensions we use for health purposes is very important. Particle size controls the surface area and therefore the effectiveness of the colloidal silver suspension."
For this reason particle surface area is the single most important property of colloidal silver. It is not uncommon for non-technical readers to mistaken believe that the concentration (ppm) of silver is the most important property. Companies selling silver protein type products will advertise very high values of silver concentration with the explanation that higher ppm concentrations are more effective but that is simply not true. In fact silver protein products have very low values of particle surface area owing to the very large size particles present in those products.
Colloid particle surface area increases as the concentration of metal particles increases. Colloids that have the highest percentage of their metal content in the form of nanoparticles will have the highest particle surface area. Therefore, colloids that are mostly ionic silver will have a low particle surface area since most of the metal content is in the form of metal ions not nanoparticles.
Colloid particle surface area increases as the particle size decreases. The highest particle surface area is achieved when there is a high concentration of nanometer or sub-nanometer sized particles. While this is the desired result, it is also the most difficult to achieve. Colloids containing high concentrations of large particles as found in silver protein products will have low particle surface area.
Ratio of surface area to mass is an expression of how efficiently a given mass of silver (concentration) is able to provide particle surface area. This ratio is calculated by dividing the particle surface area (sq. cm) by the mass (mg/L). For Mesosilver this value would be 5.23 (104.7/20). The higher this value is the more efficiently the silver is being utilized to increase the particle surface area (effectiveness) of the colloid. To put this value in perspective, a typical ionic silver product has a surface area to mass ratio of about 0.021 and a typical silver protein product has a ratio of about 0.024. The ratio for Mesosilver over 200 times greater than either of these product types. In fact no other colloidal silver product has a surface area to mass ratio that even comes close to Mesosilver.
Colloidal silver effectiveness and bioavailability
Bioavailability of colloidal silver expresses the extent to which the colloidal silver arrives in the bloodstream unchanged in form. Silver nanoparticles are what provide the particle surface area and also constitute the silver that is able to enter the bloodstream unchanged in form providing the high bioavailability. Products that are mostly ionic silver have low bioavailability. Silver ions cannot enter the bloodstream unchanged because they combine with chloride in the body and form silver chloride, an insoluble salt. For more see: Colloidal Silver Bioavailability
Introducing colloidal silver into the body
It is the combination of small particle size and high particle concentration that produces the high particle surface area and high bioavailability for maximum effectiveness in a colloidal silver product. The only product offering this powerful combination of properties is Mesosilver.
Ingestion of Colloidal Silver
By taking orally (drinking) the silver colloid enters the stomach and then the small intestines. Most of the absorption of the silver particles takes place in the small intestines. The silver particles pass through the lining the small intestines directly into the bloodstream where they circulate to all parts of the body. The particles are eventually removed from the bloodstream by the kidneys and are passed out of the body as waste. See In the bloodstream for more details.
Colloidal Silver In The Bloodstream
The effectiveness of silver particles that circulate in the bloodstream is to a large extent determined by the particle surface area that is available. High particle surface area colloids have most of their silver content contained in the silver particles. The high concentration of particles is in the form of nanometer sized silver particles which presents the highest surface area to the environment in which the colloid is present.
Powerful Combination of Properties
Mesosilver combines the smallest nanometer size particles and the highest particle concentration, a powerful combination of properties, to produce a colloidal silver product that has the highest particle surface area of any colloidal silver product ever tested. The Comparison Table Below shows how the particle surface area of Mesosilver compares to other products.
Particle Surface Area Comparison Table
Particle surface area is the property of a colloid that translates directly to the ability of the colloid to react with its environment. Effectiveness of colloids is predicated on exposing the largest possible surface area of the metal particles to the areas of interest. The importance of colloid particle surface area cannot be over emphasized. It is the single most important attribute for determining how effectively the colloidal particles will interact with their environment inside the human body.
In his booklet "Silver Colloids", Professor Ronald Gibbs wrote "The size of the particles in the colloidal silver suspensions we use for health purposes is very important. Particle size controls the surface area and therefore the effectiveness of the colloidal silver suspension."
In this context, effectiveness is defined as the ability of the colloid to interact with its environment, just as in the world of chemistry, where surface area determines how well substances react with one another. For a more complete discussion of the rationale for comparing colloidal silver products using particle surface area as a single valued metric see: Comparing Colloidal Silver Products.
The table below shows the particle surface area values for various colloidal silver products for comparative purposes. A home hobbyist colloidal silver generator is displayed on the first line of the table to show a representative sample of home made ionic silver produced using the electrolysis process.
Particle Surface Area is expressed in square centimeters per milliliter (mL) of colloidal solution.
Efficiency Index: Effective surface area per unit of concentration. Particle Surface Area (cm2/mL) per ppm X 1000. This value relates how efficiently surface area is generated per unit of concentration (ppm).
Particle Surface Area Comparison Table
Home Brewed w/ SG-7
Silver Shield Colloidal Silver
Silver Biotics 10
New Silver Solution
Sovereign Silver 10
Ultra Pure Col. Silver 35
ACS 200 Adv. Cell. Sil. 200 ppm
Futurebiotics Adv. Col. Silver 30
Int. Pharm. Invive 50
Electra Clear Col. Silver 10
Source Naturals Col. Silver 30
Kelly Colloidal Silver 20
Innovative Natural Products 500
Utopia Advanced. Col. Silver 20
MesoSilver 20 ppm has the highest particle surface area of any product tested.
Click for more detailed information and comparisons to extend your research into Colloidal Silver
Mesosilver is the Most Effective Colloidal Silver
Many products are advertised as being colloidal silver, but in fact are mostly ionic silver solutions. A true silver colloid consists mostly of silver particles. Mesosilver has the highest percentage of it's silver content in the form of sub-nanometer silver particles, not silver ions. The surface area of the silver particles is the key to colloidal effectiveness.
What is the Active Ingredient in Mesosilver?
Mesosilver is 0.9999 pure silver sub-nanometer sized particles suspended in pure deionized water. This combination is called colloidal silver. The silver nanoparticles in Mesosilver typically measure 0.65 nanometers or less in diameter, which is slightly larger than twice the diameter of an atom of silver. Each silver nanoparticle consists of approximately 9 silver atoms. Because these silver particles are so small and the concentration of particles is high, the result is a silver colloid with a very high particle surface area. In the world of chemistry, surface area determines how effectively a substance will react with its environment. Silver particles are non-toxic to humans.
Particle surface area increases as the particle size decreases. The highest particle surface area is achieved when there is a high concentration of nanometer or sub-nanometer sized particles. While this is the desired result, it is also the most difficult to achieve. Colloids containing high concentrations of large particles as found in silver protein products will have low particle surface area.
To better understand the effect that particle size has on surface area we will consider a U.S. Silver Dollar. The silver dollar contains 26.96 grams of coin silver and has a nominal diameter of 40 mm (1.574 inches). The total surface area of a silver dollar is approximately 27.70 square centimeters. If the same 26.96 grams of coin silver were divided into particles 1 nanometer in diameter, the total surface area of those particles would be 11,400 square meters which is equal to 122,708 square feet, or 2.817 acres. When the amount of coin silver contained in a silver dollar is rendered into 1 nm particles, the surface area of those particles is 4.115 million times greater than the surface area of the silver dollar.
The powerful combination of properties!
Mesosilver combines small particle size and high particle concentration, a powerful combination of properties, to produce a colloidal silver product that has the highest particle surface area of any colloidal silver product ever tested. The Comparison Table Below shows how the particle surface area of Mesosilver compares to other products.
Feeling Worse Before Feeling Better?
Some users experience a Herxheimer reaction when using colloidal silver. Simply stated, it is a reaction that occurs when the body is detoxifying and the released toxins which can produce headaches, body ache, joint pain, sweating, general malaise, sore throat, nausea and/or flu-like symptoms.
You should not use this product if you are allergic to silver!
Allergic reactions to silver, while not unheard of, are uncommon. Someone having an allergic reaction to silver would not be able to handle a metallic silver object such as silver jewelry without causing an allergic reaction. Those who are uncertain if they are allergic to silver should apply a few drops to the back of the hand to see if an allergic reaction results. If you do not see a reaction within 30 minutes you can be fairly certain that you are not allergic to silver.
The dosage for Mesosilver is typically between one teaspoon (5mL) and one tablespoon (15mL) daily to help maintain health. One to four tablespoons taken 4 times per day may be taken to help fortify the immune system when needed. Actual dosage will vary based on individual needs. A 500 mL bottle will provide a one month supply when used at a dosage of one tablespoon per day
Unlike most colloidal silver products, Mesosilver is a clear amber colored liquid, looking like dark iced tea. It is the very high concentration of Mesosilver particles, not size or contamination, that gives Mesosilver its distinctive coloration.
Previously, it was thought that such a dark color indicated the presence of large silver particles, which is the case for colloidal silver produced by methods other than the mesoprocess. The small size of the silver particles is confirmed by the use of a state-of-the-art scientific instrument designed specifically for measuring such small particles. Produced by Malvern Instruments, Ltd. of the United Kingdom, the High Performance Particle Sizer (HPPS) is capable of measuring colloidal particles down to 0.6 nm diameter. The particle size report from the Malvern HPPS indicates that the size of the silver particles in Mesosilver is 0.65 nm in diameter, or only slightly more than two times the diameter of a silver atom making these particles the smallest silver particles of any product on the market.
Once the bottle is opened the color of Mesosilver may change to gray depending on the atmospheric pollutants found in the air. This color change does not indicate a problem with the product and is not cause for concern. The effectiveness is not effected. The color change to gray is commonly found in large cities like Boston, New York, Chicago, Los Angeles, Detroit, Denver, and in many cities in California.
Get yourself and your family started here with a program that makes sense and please stay in touch. Your health is important to us so please make it important to you. Remember "The Time is Always Now."
Robert S. Fox, Nutritional Consultant
Phone: 201-944-7757 Off - 201-362-5619 Cell